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产品目录

兔抗cMet抗体图片
产品货号:
YT704
中文名称:
兔抗cMet抗体
英文名称:
cMet Rabbit Polyclonal Antibody
产品规格:
50μl
发货周期:
1~3天
产品价格:
询价
本品为来源于兔的抗cMet的多克隆抗体。
宿主:兔
克隆性:多克隆抗体
用途:WB,FC, IHC,ICC, IF
交叉反应性:人,小鼠,大鼠
分子量:153KDa
推荐稀释比例:WB(1:1000),IF(1:200),IHC(1:200),ICC(1:200),FC(1:100-1:200)

About this Antibody
Name cMet Rabbit Polyclonal Antibody
Category Polyclonal antibody(pAb); Primary antibody
Isotype IgG
Purification Peptide affinity purified
About the Immunogen
Immunogen This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of cMet.
Gene ID 4233
SwissProt P08581
Synonyms EC 2.7.10.1; HGF receptor; HGF-SF receptor; Hepatocyte growth factor receptor precursor; Met proto- oncogene tyrosine kinase; c-met; kinase EC 2.7.10.1; HGF receptor; HGF-SF receptor; Hepatocyte growth factor receptor precursor; Met proto- oncogene tyros
Category RTK
Background c-Met (MET or MNNG HOS Transforming gene) is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). MET is a membrane receptor that is essential for embryonic development and wound healing. Hepatocyte growth factor (HGF) is the only known ligand of the MET receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF is restricted to cells of mesenchymal origin. Upon HGF stimulation, MET induces several biological responses that collectively give rise to a program known as invasive growth. Abnormal MET activation in cancer correlates with poor prognosis, where aberrantly active MET triggers tumor growth, formation of new blood vessels (angiogenesis) that supply the tumor with nutrients, and cancer spread to other organs (metastasis). MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain.


注意事项:
1. 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验,请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体,包括已经使用过的稀释抗体,请4℃保存。
2. 回收后重复使用的抗体,使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象,可以10,000g离心1-3分钟,取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况,则可以考虑废弃该抗体。
3. 提供的Western一抗稀释液也可以用于免疫荧光(IF)、免疫组化(IHC)、免疫细胞化学(ICC)等适当用途。如果希望获得最佳的检测效果,请考虑使用上述检测专用的一抗稀释液。

储存条件:-20℃,有效期一年。
相关搜索:兔抗cMet抗体cMet Rabbit Polyclonal Antibody
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